Seven-time champion Rafael Nadal is out of the Italian Open after a straight-set loss to Dominic Thiem in the quarter-finals in Rome.
Thiem dominated this encounter, frequently forcing Nadal behind the baseline to set up a 6-4 6-3 win.
The 30-year-old Spaniard was previously unbeaten on clay this year, having won 17 straight matches.
That run included victories over Austria’s Thiem, 23, in the Barcelona Open and Madrid Open finals.
He will face either world number two Novak Djokovic or Juan Martin del Potro in the semi-finals.