New Delhi: China’s Sinovac Biotech appeared to be safe in a late-stage clinical trial in Brazil, preliminary results showed.  Sao Paulo’s Butantan Institute, one of Brazil’s leading biomedical research centers, which is carrying out the Phase III tests, said the two-dose vaccine, called CoronaVac, proved to be safe in a trial so far involving 9,000 volunteers. Also Read - Serum Institute, Bharat Biotech to Begin Late-Stage Trial of Intranasal Covid-19 Vaccine Soon

Quoting the institute authorities, news agency Reuters reported that there were no severe adverse reactions to the vaccine, with 20% of the volunteers reporting mild pain from the injection while 15% reported headaches after the first dose, dropping to 10% for the second. Less than 5% reported nausea or tiredness, and even less had muscle aches. Also Read - 200-300 Million Doses of COVID-19 Vaccine Likely to be Ready by December-end: SII

The World Health Organisation (WHO) had informed 44 coronavirus vaccine candidates are in clinical trials, with another 154 in development.

Meanwhile,  the overall number of global coronavirus cases has increased to 40.3 million, while the deaths have soared to 1,117,430. As of Tuesday morning, the total number of cases stood at 40,333,146, the University’s Center for Systems Science and Engineering (CSSE) revealed in its latest update.

The US remains the worst-hit country with the world’s highest number of cases and deaths at 8,210,849 and 220,095, respectively. India comes in second place in terms of cases at 7,550,273, while the country’s death toll soared to 114,610.

(With agency inputs)