New Delhi: The World Health Organization (WHO) guidelines panel on Friday advised against the use of antiviral drug remdesivir for treating Covid-19 patients, saying there’s no evidence it improves survival rate or avoids the need for breathing machines. Also Read - US FDA Approves Remdesivir as First Drug to Treat Coronavirus

The WHO’s warning comes as health officials around the world are clashing over the use of certain drugs for Covid-19, leading to different treatment options for patients depending on where they live. Also Read - Does Remdesivir Work in Covid-19 Treatment? WHO Trial Says No Cut in Hospital Stay or Mortality

“The panel found a lack of evidence that remdesivir improved outcomes that matter to patients such as reduced mortality, need for mechanical ventilation, time to clinical improvement, and others,” Xinhua news agency quoted the WHO’s Guideline Development Group (GDG) panel. Also Read - How Remdesivir Can Save Lives in Nations With Lower Hospital Capacity

“Any beneficial effects of remdesivir, if they do exist, are likely to be small and the possibility of important harm remains,” the panel added.

The WHO recommendation, published in the British Medical Journal, was based on an evidence review that included data from four international randomised trials among more than 7,000 hospitalised patients.

After reviewing the evidence, the panel concluded that remdesivir has no meaningful effect on death rate or other important outcomes for patients.

“Especially given the costs and resource implications associated with remdesivir… The panel felt the responsibility should be on demonstrating evidence of efficacy, which is not established by the currently available data,” it said.

The antiviral is one of only two medicines currently authorised to treat Covid-19 patients across the world.

It has been approval for use in the US, the European Union and other countries after initial research found it may shorten recovery time in some Covid-19 patients.

Made by the US company Gilead, remdesivir is extremely expensive and is given intravenously.

Gilead said last month that the drug had boosted its third quarter sales by about $900 million.

The overall number of global coronavirus cases has topped 56.8 million, while the deaths have surged to more than 1.35 million, according to the Johns Hopkins University.

In its latest update on Friday, the University’s Center for Systems Science and Engineering (CSSE) revealed that the current global caseload and death toll stood at 56,817,667 and 1,358,489, respectively.

The US is the worst-hit country with the world’s highest number of cases and deaths at 11,710,084 and 252,484, respectively, according to the CSSE.

(With IANS inputs)