Defending champion Andy Murray has been drawn in the same half of the Wimbledon draw as Rafael Nadal and Stan Wawrinka, who, depending on their performances at The Championships, could usurp Murray at No. 1 in the Emirates ATP Rankings.
Novak Djokovic, who is also in contention for a return to the top spot, is in the bottom half of the 128-man draw with Roger Federer and last year’s finalist Milos Raonic.
Murray will begin the defence of his Wimbledon title against a qualifier or a lucky loser on Monday.
The 30-year-old Scot, who won the tournament for a second time last year, is the top seed and will begin on Centre Court.
It means Murray could potentially face British qualifier and world number 855 Alex Ward. Seven-time champion Roger Federer faces Alexandr Dolgopolov in the first round.
Djokovic, seeded two despite his world ranking having slipped to four after a slump which has seen him lose possession of all four majors, has a fourth round meeting lined-up with Gael Monfils.
Djokovic’s meeting with del Potro could prove the highlight of the first week. The Serb defeated the giant Argentine in a memorable five-setter in the semi-finals in 2013 while Del Potro triumphed over the Serb at the Olympics last year.
Federer has a possible last-16 duel with Grigor Dimitrov and quarter-final against either 2016 runner-up Milos Raonic or Alexander Zverev who was swept aside by the Swiss star in the Halle final last week where the veteran claimed a ninth title.
Nadal, meanwhile, has big-serving Gilles Muller as a possible last-16 foe and Japan’s Kei Nishikori or former US Open winner Marin Cilic in the last eight.
It is possible that Nadal and Federer could meet in the final for the fourth time after 2006, 2007 and 2008.